TM4SF1 anticorps (N-Term)

N° du produit ABIN783425

Détail du produit anti-TM4SF1 anticorps

Antigène: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TM4SF1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TM4SF1 at N-term. At least three isoforms of TM4SF1 are known to exist, this antibody will recognize only the two largest isoforms. TM4SF1 antibody is predicted to not cross-react with other tetraspanin proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the amino terminus of human TM4SF1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur TM4SF1

Antigène: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Autre désignation: TM4SF1 (TM4SF1 Produits)

Synonymes: anticorps MGC85546, anticorps h-l6, anticorps m3s1, anticorps taal6, anticorps H-L6, anticorps L6, anticorps M3S1, anticorps TAAL6, anticorps MM3, anticorps M3s1, anticorps transmembrane 4 L six family member 1, anticorps transmembrane 4 L six family member 1 S homeolog, anticorps transmembrane 4 superfamily member 1, anticorps TM4SF1, anticorps tm4sf1.S, anticorps tm4sf1, anticorps Tm4sf1

Sujet: TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.Synonyms: M3S1, Membrane component surface marker 1, TAAL6, Transmembrane 4 L6 family member 1, Tumor-associated antigen L6

ID gène: 4071

NCBI Accession: NP_055035

UniProt: P30408