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VPS53 anticorps (C-Term)

VPS53 Reactivité: Humain, Souris, Rat WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN783564
  • Antigène Voir toutes VPS53 Anticorps
    VPS53 (Vacuolar Protein Sorting 53 Homolog (VPS53))
    Épitope
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 20
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 18
    • 2
    Lapin
    Clonalité
    • 20
    Polyclonal
    Conjugué
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp VPS53 est non-conjugé
    Application
    • 13
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects VPS53 at C-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    18 amino acid peptide from near the carboxy terminus of human VPS53
    Top Product
    Discover our top product VPS53 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Antigène
    VPS53 (Vacuolar Protein Sorting 53 Homolog (VPS53))
    Autre désignation
    VPS53 (VPS53 Produits)
    Synonymes
    anticorps wu:fb77d11, anticorps zgc:103741, anticorps DKFZp469N152, anticorps 2010002A08Rik, anticorps 2310040I21Rik, anticorps 3100002B05Rik, anticorps Hccs1, anticorps HCCS1, anticorps hVps53L, anticorps pp13624, anticorps RGD1311391, anticorps VPS53, GARP complex subunit, anticorps vacuolar protein sorting 53 homolog (S. cerevisiae), anticorps vacuolar protein sorting 53, anticorps VPS53 GARP complex subunit, anticorps VPS53, anticorps vps53, anticorps PAAG_00802, anticorps MCYG_06020, anticorps VDBG_07188, anticorps MGYG_05943, anticorps Vps53
    Sujet
    The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes. The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits: VPS52, VPS53, and VPS54. Depletion of any of these three proteins, such as by RNAi, impairs the retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell, suggesting that VPS53 may be an important drug target in HIV treatment. At least five isoforms of VPS53 are known to exist.Synonyms: PP13624, Vacuolar protein sorting-associated protein 53 homolog
    ID gène
    55275
    NCBI Accession
    NP_001121631
    UniProt
    Q5VIR6
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