SCUBE1 anticorps (Center)

N° du produit ABIN783649

Détail du produit anti-SCUBE1 anticorps

Antigène: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCUBE1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the center of human SCUBE1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: 14 amino acid peptide near the center of human SCUBE1

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur SCUBE1

Antigène: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Autre désignation: SCUBE1 (SCUBE1 Produits)

Synonymes: anticorps 7330410C13Rik, anticorps A630023E24Rik, anticorps signal peptide, CUB domain and EGF like domain containing 1, anticorps signal peptide, CUB domain, EGF-like 1, anticorps SCUBE1, anticorps Scube1

Sujet: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity, genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.Synonyms: Signal peptide CUB and EGF-like domain-containing protein 1

ID gène: 80274

NCBI Accession: NP_766638

UniProt: Q8IWY4