Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

FRMPD1 anticorps (C-Term)

FRMPD1 Reactivité: Humain WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499857
  • Antigène Voir toutes FRMPD1 Anticorps
    FRMPD1 (FERM and PDZ Domain Containing 1 (FRMPD1))
    Épitope
    • 15
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    Humain
    Hôte
    • 16
    • 2
    • 1
    Lapin
    Clonalité
    • 19
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FRMPD1 est non-conjugé
    Application
    • 18
    • 13
    • 13
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    FRMPD1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human FRMPD1.
    Isotype
    IgG
    Top Product
    Discover our top product FRMPD1 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: 1 - 2 μg/mL. Immunofluorescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at -20 °C.
  • Antigène
    FRMPD1 (FERM and PDZ Domain Containing 1 (FRMPD1))
    Autre désignation
    FRMPD1 (FRMPD1 Produits)
    Synonymes
    anticorps FRMD2, anticorps BC031840, anticorps mKIAA0967, anticorps FERM and PDZ domain containing 1, anticorps FRMPD1, anticorps Frmpd1
    Sujet
    The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD1 was initially identified through a yeast two-hybrid screening with Activator of G-protein signaling 3 (AGS3), a protein that acts to stabilize the GDP-bound conformation of Gai, as the bait. FRMPD1 binds to the tetratricopeptide repeat of AGS3 and stabilizes AGS3 in a membrane environment. Suppression of FRMPD1 in Cath.a-differentiated neuronal cells decreased the level of endogenous AGS3 in membrane fractions by ~50 % and enhanced the inhibition of forskolin-induced increases in cAMP. Co-immunoprecipitation studies indicate that the interaction of AGS3 with FRMPD1 is mutually exclusive with the interaction of AGS3 with Gai3, suggesting that FRMPD1 may position AGS3 in the membrane where it can then interact with Galphai.Synonyms: FERM and PDZ domain-containing protein 1, FERM domain-containing protein 2, FRMD2, KIAA0967
    ID gène
    22844
    NCBI Accession
    NP_055722
    UniProt
    Q5SYB0
Vous êtes ici:
Support technique