Gastrin anticorps (GAST) (C-Term)

Details for Product anti-GAST Antibody No. ABIN5554816
Antigène
  • GAS
  • Gas
  • PPG34
  • GAST
  • gastrin
  • GAST
  • Gast
Épitope
C-Term
8
8
7
4
3
3
3
2
2
2
2
1
1
1
1
Reactivité
Humain, Souris
125
48
47
6
3
3
2
2
1
1
1
Hôte
Lapin
133
13
5
Clonalité
Polyclonal
Conjugué
Cet anticorp Gastrin est non-conjugé
12
10
3
3
3
3
3
3
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
84
69
33
26
24
20
18
18
14
13
6
3
3
2
1
1
Options
Immunogène GAS antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human GAS.
Isotype IgG
Purification Affinity chromatography purified via peptide column
Plasmids, Primers & others Plasmids, Primers & others Gastrin products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation GAS (GAST Antibody Extrait)
Sujet Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERa), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERa is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.Synonyms: Glutamate-rich coactivator interacting with SRC1, PA1, PTIP-associated 1 protein
ID gène 2716513
NCBI Accession NP_078792
UniProt P08315
Indications d'application ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock -20 °C
Stockage commentaire Store the antibody (in aliquots) at -20 °C.
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