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HRK anticorps (Center)

HRK Reactivité: Humain, Souris WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499950
  • Antigène Voir toutes HRK Anticorps
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    Épitope
    • 15
    • 13
    • 7
    • 2
    • 1
    • 1
    Center
    Reactivité
    • 28
    • 22
    • 18
    • 2
    • 2
    • 2
    • 1
    Humain, Souris
    Hôte
    • 43
    Lapin
    Clonalité
    • 43
    Polyclonal
    Conjugué
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HRK est non-conjugé
    Application
    • 18
    • 14
    • 13
    • 13
    • 8
    • 5
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody recognizes HRK.
    Purification
    Peptide Affinity Chromatography
    Immunogène
    HRK antibody was raised against a 15 amino acid peptide from near the center of Human Hrk.
    Isotype
    IgG
    Top Product
    Discover our top product HRK Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: 2.5-5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    Autre désignation
    Harakiri / HRK (HRK Produits)
    Synonymes
    anticorps DP5, anticorps HARAKIRI, anticorps AI838259, anticorps Bid3, anticorps harakiri, anticorps Dp5, anticorps harakiri, BCL2 interacting protein, anticorps harakiri, BCL2 interacting protein (contains only BH3 domain), anticorps HRK, anticorps Hrk
    Sujet
    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Hrk, a pro-apoptotic member of the Bcl-2 homology domain-3 (BH3)-only group of the Bcl-2 family of proteins, was also identified as novel protein induced during programmed neuronal death. It lacks significant homology to other Bcl-2 family members except for an 8-amino acid region that is similar to the BH3 motif of Bik. Hrk regulates apoptosis through interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL via this domain. It does not interact with the pro-apoptotic proteins Bax, Bak, or Bcl-XS. Hrk localizes to mitochondrial membranes in a pattern similar to that previously reported for Bcl-2 and Bcl-XL. Despite its predicted molecular weight, Hrk often migrates at 12-15 kDa.Synonyms: Activator of apoptosis harakiri, BH3-interacting domain-containing protein 3, BID3, Neuronal death protein DP5
    ID gène
    8739
    NCBI Accession
    NP_003797
    UniProt
    O00198
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