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FBXO43 anticorps (C-Term)

FBXO43 Reactivité: Humain WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499984
  • Antigène Voir toutes FBXO43 Anticorps
    FBXO43 (F-Box Protein 43 (FBXO43))
    Épitope
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 10
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 9
    • 2
    • 1
    Lapin
    Clonalité
    • 10
    • 2
    Polyclonal
    Conjugué
    • 12
    Cet anticorp FBXO43 est non-conjugé
    Application
    • 10
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    IL-1RAcP antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of IL-1RAcP, which differs from the sequence of mouse origin by three amino acids. It has no cross activity to other member in the IL-1 receptor family.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    Human IL-1RAcP (C-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product FBXO43 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: 1/500 to 1/1000. An approximately 66 kDa band can be detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    FBXO43 (F-Box Protein 43 (FBXO43))
    Autre désignation
    FBXO43 (FBXO43 Produits)
    Synonymes
    anticorps EMI2, anticorps ERP1, anticorps FBX43, anticorps 4930533G20Rik, anticorps Emi2, anticorps emi2, anticorps erp1, anticorps Xerp1, anticorps zgc:66488, anticorps F-box protein 43, anticorps F-box protein 43 L homeolog, anticorps FBXO43, anticorps Fbxo43, anticorps fbxo43, anticorps fbxo43.L
    Sujet
    The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I(IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1).IL-1 RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kappaB inducing kinae (NIK) and of NF-kappaB, recruites to the IL-1R complex through IL-1 RAcP(2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP(3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.Synonyms: EMI2, Endogenous meiotic inhibitor 2, F-box only protein 43, FBP5B
    ID gène
    100101275
    UniProt
    Q8AXF4
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