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Junctophilin 3 anticorps (C-Term)

JPH3 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500100
  • Antigène Voir toutes Junctophilin 3 (JPH3) Anticorps
    Junctophilin 3 (JPH3)
    Épitope
    • 15
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 27
    • 13
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 33
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Junctophilin 3 est non-conjugé
    Application
    • 28
    • 16
    • 13
    • 13
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects JPH3 at C-term.
    Purification
    Peptide affinity chromatography
    Immunogène
    JPH3 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human JPH3.
    Isotype
    IgG
    Top Product
    Discover our top product JPH3 Anticorps primaire
  • Indications d'application
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Junctophilin 3 (JPH3)
    Autre désignation
    Junctophilin-3 / JPH3 (JPH3 Produits)
    Synonymes
    anticorps CAGL237, anticorps HDL2, anticorps JP-3, anticorps JP3, anticorps TNRC22, anticorps Jp3, anticorps fc26e06, anticorps si:ch211-255l14.9, anticorps wu:fc26e06, anticorps junctophilin 3, anticorps JPH3, anticorps Jph3, anticorps jph3
    Sujet
    Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions. A repeat expansion in JPH3 is associated with Huntington disease-like 2. At least two isoforms of JPH3 are known to exist.Synonyms: JP3, Junctophilin type 3, TNRC22, Trinucleotide repeat-containing gene 22 protein
    ID gène
    57338
    NCBI Accession
    NP_065706
    UniProt
    Q8WXH2
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