PPAPDC1B anticorps (N-Term)

N° du produit ABIN500529

Détail du produit anti-PPAPDC1B anticorps

Antigène: PPAPDC1B (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1B (PPAPDC1B))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPAPDC1B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PPAPDC1B.

Purification: Peptide affinity chromatography

Immunogène: PPAPDC1B antibody was raised against a 14 amino acid peptide near the amino terminus of human PPAPDC1B.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PPAPDC1B

Antigène: PPAPDC1B (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1B (PPAPDC1B))

Autre désignation: PPAPDC1B (PPAPDC1B Produits)

Synonymes: anticorps PPAPDC1B, anticorps DPPL1, anticorps HTPAP, anticorps 1810019D05Rik, anticorps 2310022A04Rik, anticorps AW045471, anticorps Ppapdc1, anticorps phospholipid phosphatase 5, anticorps PLPP5, anticorps plpp5, anticorps Plpp5

Sujet: Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways, including the JAK-Stat3, MAP kinase, and PKC pathways. PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22.Synonyms: DPPL1, HTPAP, Phosphatidate phosphatase PPAPDC1B, Phosphatidic acid phosphatase type 2 domain-containing protein 1B

ID gène: 84513

NCBI Accession: NP_001096029

UniProt: Q8NEB5