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MEX3D anticorps (Center)

MEX3D Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500616
  • Antigène Voir toutes MEX3D Anticorps
    MEX3D (Mex-3 Homolog D (MEX3D))
    Épitope
    • 15
    • 1
    • 1
    Center
    Reactivité
    • 17
    • 16
    • 15
    Humain
    Hôte
    • 17
    • 1
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MEX3D est non-conjugé
    Application
    • 18
    • 13
    • 13
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects Rkhd1.
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Peptide affinity chromatography
    Immunogène
    Rkhd1 antibody was raised against a 15 amino acid peptide from near the center of human Rkhd1.
    Isotype
    IgG
    Top Product
    Discover our top product MEX3D Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    MEX3D (Mex-3 Homolog D (MEX3D))
    Autre désignation
    MEX3D / RKHD1 (MEX3D Produits)
    Synonymes
    anticorps RKHD1, anticorps MEX3D, anticorps rkhd1, anticorps mex3, anticorps tino, anticorps rnf193, anticorps ok/sw-cl.4, anticorps MEX-3D, anticorps MEX3, anticorps OK/SW-cl.4, anticorps RNF193, anticorps TINO, anticorps BC059858, anticorps Rkhd1, anticorps mex-3 RNA binding family member D, anticorps mex-3 RNA binding family member D L homeolog, anticorps mex3 RNA binding family member D, anticorps MEX3D, anticorps mex3d.L, anticorps mex3d, anticorps Mex3d
    Sujet
    Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression. Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.Synonyms: KIAA2031, RING finger and KH domain-containing protein 1, RING finger protein 193, RNA-binding protein MEX3D, RNF193, TINO
    ID gène
    399664
    UniProt
    Q86XN8
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