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FBXL20 anticorps (N-Term)

FBXL20 Reactivité: Humain, Rat, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500692
  • Antigène Voir toutes FBXL20 Anticorps
    FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
    Épitope
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 14
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    Humain, Rat, Souris
    Hôte
    • 11
    • 2
    • 1
    Lapin
    Clonalité
    • 12
    • 2
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    Cet anticorp FBXL20 est non-conjugé
    Application
    • 9
    • 9
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects FBXL20 at N-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    FBXL20 antibody was raised against a 18 amino acid peptide near the amino terminus of the human FBXL20.
    Isotype
    IgG
    Top Product
    Discover our top product FBXL20 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
    Autre désignation
    FBXL20 (FBXL20 Produits)
    Synonymes
    anticorps Fbl2, anticorps Fbl20, anticorps fbl20, anticorps MGC81000, anticorps scrapper, anticorps FBL2, anticorps 2610511F20Rik, anticorps 4632423N09Rik, anticorps AI849362, anticorps AL117906, anticorps C86145, anticorps Scr, anticorps mKIAA4147, anticorps FBXL2, anticorps Fbxl2, anticorps F-box and leucine rich repeat protein 20, anticorps F-box and leucine-rich repeat protein 20 L homeolog, anticorps F-box and leucine-rich repeat protein 20, anticorps F-box/LRR-repeat protein 20, anticorps putative fbxl20, anticorps F-box and leucine rich repeat protein 2, anticorps FBXL20, anticorps fbxl20.L, anticorps LOAG_14232, anticorps LOC100080065, anticorps Smp_097020.1, anticorps FBXL2, anticorps Fbxl20
    Sujet
    Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane. Scrapper has orthologs in C. elegans, D. melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species. Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission. This identifies protein degradation as a mechanism for holding synaptic communication in check.Synonyms: F-box and leucine-rich repeat protein 20, F-box/LRR-repeat protein 2-like, F-box/LRR-repeat protein 20, FBL2
    ID gène
    84961
    NCBI Accession
    NP_116264
    UniProt
    Q96IG2
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