USP6 anticorps (C-Term)
-
- Antigène Voir toutes USP6 Anticorps
- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
-
Épitope
- C-Term
-
Reactivité
- Humain
-
Hôte
- Chèvre
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp USP6 est non-conjugé
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Séquence
- KISPLHHLQM ECSP
- Specificité
- This antibody recognizes USP6/TRE2/TRE17
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- Immunogène
- Peptide with sequence from the C Terminus of the protein sequence according to NP_004496.1. Genename: USP6
- Top Product
- Discover our top product USP6 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
- Autre désignation
- USP6 / TRE2 (USP6 Produits)
- Synonymes
- anticorps HRP1, anticorps TRE2, anticorps TRE17, anticorps Tre-2, anticorps USP6-short, anticorps ubiquitin specific peptidase 6, anticorps ubiquitin carboxyl-terminal hydrolase 6, anticorps Ubiquitin carboxyl-terminal hydrolase 6, putative, anticorps USP6, anticorps CNG04540, anticorps ANI_1_2152104, anticorps AOR_1_208094, anticorps MCYG_00569, anticorps CC1G_15273, anticorps MGYG_01395, anticorps CGB_G0160W, anticorps LOC100282385
- Sujet
- Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation. A chromosomal aberration involving USP6 is a common genetic feature of aneurysmal bone cyst, a benign osseous neoplasm. Translocation t(16,17)(q22,p13) with CDH11. The translocation generates a fusion gene in which the strong CDH11 promoter is fused to the entire USP6 coding sequence, resulting in USP6 transcriptional up-regulation.Synonyms: Deubiquitinating enzyme 6, HRP1, TRE-2, Ubiquitin carboxyl-terminal hydrolase 6, Ubiquitin thioesterase 6, Ubiquitin-specific-processing protease 6
- ID gène
- 9098
- NCBI Accession
- NP_004496
-