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TET2 anticorps (N-Term)

TET2 Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1450172
  • Antigène Voir toutes TET2 Anticorps
    TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
    Épitope
    • 16
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 46
    • 15
    • 6
    Humain
    Hôte
    • 40
    • 8
    • 2
    Lapin
    Clonalité
    • 42
    • 8
    Polyclonal
    Conjugué
    • 32
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TET2 est non-conjugé
    Application
    • 38
    • 23
    • 11
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    18 amino acid synthetic peptide near the amino terminus of Human TET2
    Isotype
    IgG
    Top Product
    Discover our top product TET2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
    Autre désignation
    TET2 (TET2 Produits)
    Synonymes
    anticorps KIAA1546, anticorps MDS, anticorps Ayu17-449, anticorps E130014J05Rik, anticorps mKIAA1546, anticorps RGD1311625, anticorps tet methylcytosine dioxygenase 2, anticorps TET2, anticorps Tet2
    Sujet
    TET2, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. It is a candidate tumor suppressor gene reported to be mutated in approximately 14 % of patients with JAK2V617F-positive myeloproliferative neoplasms, and can be mutated in other hematopoietic disorders such as myelodysplastic syndromes, acute myeloid leukemia, and chronic myelomonocytic leukemia. Analysis of the TET2 and JAK2 mutations in these neoplasms suggests that mutations in TET2 do not represent a predisposition for acquiring mutations in JAK2.Synonyms: KIAA1546, Methylcytosine dioxygenase TET2
    ID gène
    54790
    NCBI Accession
    NP_001120680
    Pathways
    L'effet Warburg
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