SERPINA1
Reactivité: Humain
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Reconstitution
Restore with 2.0 mL of deionized water or equivalent.
Concentration
90.0 mg/mL (prior to lyophilization by refractometry)
Buffer
0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % Sodium Azide, None
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Dilute only prior to immediate use. Avoid cycles of freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store vial at 2-8 °C prior to restoration. Restore with 2.0 ml of deionized water (or equivalent). Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid. For extended storage aliquot contents and freeze at -20 °C or below.
Schachner, Golderer, Sarg, Lindner, Bonaros, Mikuz, Laufer, Werner: "The amounts of alpha 1 antitrypsin protein are reduced in the vascular wall of the acutely dissected human ascending aorta." dans: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 37, Issue 3, pp. 684-90, (2011) (PubMed).
Antigène
SERPINA1
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))
anticorps AACT, anticorps ACT, anticorps GIG25, anticorps A1AT, anticorps PI, anticorps alpha-1-PI, anticorps A1A, anticorps AAT, anticorps PI1, anticorps PRO2275, anticorps alpha1AT, anticorps Pi, anticorps Spi1, anticorps MGC64429, anticorps serpina1d, anticorps Aps, anticorps SERPINA3-5, anticorps serpin family A member 3, anticorps alpha-1-antiproteinase F precursor, anticorps serpin family A member 1, anticorps alpha-1-antitrypsin, anticorps calumenin, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5, anticorps SH2B adaptor protein 2, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog, anticorps SERPINA3, anticorps LOC100008973, anticorps SERPINA1, anticorps LOC100328621, anticorps CALU, anticorps Serpina1, anticorps serpina1.S, anticorps serpina1, anticorps SPIA5, anticorps Sh2b2, anticorps Calu, anticorps serpina1.L
Sujet
Alpha-1 Antitrypsin is a plasma protein synthesised in the liver. It consists of a single polypeptide chain and has a molecular weight of 52 kDa. A serine protease inhibitor, its primary function is the protection of lung tissue from the action of neutrophil elastase.Synonyms: AAT, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, SERPINA1