Lambda-IgLC anticorps

N° du produit ABIN5563943

Détail du produit anti-Lambda-IgLC anticorps

Antigène: Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Lambda-IgLC est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Attributs du produit: The clone HP6054 specifically binds with both soluble and membrane bound human lambda light chain of immunoglobulin but not binds with the kappa light chain or heavy chain. Lambda light chains are primarily expressed on the surface of B cells in lymphoid tissues. Each B cell expresses only one class of light chain kappa or lambda. In serum of a healthy individual, the total kappa to lambda ratio is approximately 3:1 while measuring as intact whole antibodies or 1:1.5 while measuring as free light chains. Various clinical research data claim that any highly divergent ratio of kappa to lambda indicative of neoplasm. HP6054 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.

Purification: Purified

Pureté: >95 %

Classe de qualité: GMP Grade

Immunogène: Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads

Clone: HP6054

Isotype: IgG2a kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur Lambda-IgLC

Antigène: Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

Autre désignation: Ig Lambda Light Chain (Lambda-IgLC Produits)

Sujet: The clone HP6054 specifically binds with both soluble and membrane bound human lambda light chain of immunoglobulin but not binds with the kappa light chain or heavy chain. Lambda light chains are primarily expressed on the surface of B cells in lymphoid tissues. Each B cell expresses only one class of light chain kappa or lambda. In serum of a healthy individual, the total kappa to lambda ratio is approximately 3:1 while measuring as intact whole antibodies or 1:1.5 while measuring as free light chains. Various clinical research data claim that any highly divergent ratio of kappa to lambda indicative of neoplasm. HP6054 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.