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SLC7A8 anticorps

SLC7A8 Reactivité: Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5564261
  • Antigène Voir toutes SLC7A8 Anticorps
    SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))
    Reactivité
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Souris, Rat
    Hôte
    • 9
    • 4
    Lapin
    Clonalité
    • 9
    • 4
    Polyclonal
    Conjugué
    • 13
    Cet anticorp SLC7A8 est non-conjugé
    Application
    • 12
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Recognizes mouse and rat Slc7a8. Has been reported to work in human samples (Wirth,et al.; 2009), but was not tested in-house.Detects a -50kDa Slc7a8 band in wild type mouse brain, kidney, jejunum, ileum and othertissues, which is absent in knock-out animals. ln some tissues the antibody detects anadditional unknown 38kDa band.
    Réactivité croisée (Details)
    Other species not tested.Detects a ~50 kDa Slc7a8 band in wild type mouse brain, kidney, jejunum, ileum and other tissues, which is absent in knock-out animals. In some tissues the antibody detects an additional unknown 38 kDa band.
    Purification
    Antigen affinity purified.
    Immunogène
    Synthetic peptide corresponding to a partial sequence of mouse Slc7a8 (Q9QXW9).
    Top Product
    Discover our top product SLC7A8 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 1 mg/mL BSA and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Antigène
    SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))
    Autre désignation
    Slc7a8 [Lat2] (SLC7A8 Produits)
    Synonymes
    anticorps LAT2, anticorps LPI-PC1, anticorps Lat2, anticorps Lat4, anticorps XAA2, anticorps lat2, anticorps lpi-pc1, anticorps 4F2LC-5, anticorps AA408822, anticorps si:ch211-14a17.3, anticorps si:zc14a17.3, anticorps slc7a8, anticorps solute carrier family 7 member 8, anticorps solute carrier family 7 member 8 L homeolog, anticorps solute carrier family 7 (amino acid transporter, L-type), member 8, anticorps solute carrier family 7 (cationic amino acid transporter, y+ system), member 8, anticorps solute carrier family 7 (amino acid transporter light chain, L system), member 8b, anticorps SLC7A8, anticorps Slc7a8, anticorps slc7a8.L, anticorps slc7a8, anticorps slc7a8b
    Sujet
    L-type amino acid transporter (LAT) family members are Na(+)-independent transporters, which deliver neutral amino acids into cells. The four LATs, LAT1 (SLC7A5), LAT2 (SLC7A8), LAT3 (SLC43A1) and LAT4 (SLC43A2) are responsible for the majority of cellular leucine uptake. They show increased expression in many cancers and are critical for control of protein translation and cell growth through the mTORC1 pathway. The increased transporter expression observed in cancers is regulated by transcriptional pathways such as hormone receptors, c-myc and nutrient starvation responses.
    UniProt
    Q9QXW9
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