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ABCB8 anticorps (Internal Region)

ABCB8 Reactivité: Humain, Lapin WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5596884
  • Antigène Voir toutes ABCB8 Anticorps
    ABCB8 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))
    Épitope
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 20
    • 10
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Lapin
    Hôte
    • 21
    • 1
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ABCB8 est non-conjugé
    Application
    • 13
    • 7
    • 6
    • 3
    • 2
    Western Blotting (WB), ELISA
    Réactivité croisée (Details)
    A BLAST analysis was used to suggest cross-reactivity with ABCB8 from human, mouse, and rat based on a 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known. The antibody detects ABCB8 in cell lysates.
    Purification
    Anti-ABCB8 Antibody was prepared from monospecific, delipidated and defibrinated antiserum, with addition of sodium azide to 0.01%.
    Immunogène

    Immunogen: ABCB8 was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a internal portion of human ABCB8.

    Immunogen Type: Peptide

    Isotype
    IgG
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    Discover our top product ABCB8 Anticorps primaire
  • Indications d'application

    Application Note: Anti-ABCB8 antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect band approximately 79.9 kDa in size corresponding to ABCB8 by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:250-1:500

    ELISA Dilution: 1:20,000-1:50,000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    80 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Date de péremption
    12 months
  • Antigène
    ABCB8 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))
    Autre désignation
    ABCB8 (ABCB8 Produits)
    Synonymes
    anticorps EST328128, anticorps M-ABC1, anticorps MABC1, anticorps 4833412N02Rik, anticorps AA409895, anticorps ABCB8, anticorps zgc:113037, anticorps ATP binding cassette subfamily B member 8, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 8, anticorps ABCB8, anticorps Abcb8, anticorps abcb8
    Sujet

    Synonyms: ATP-binding cassette sub-family B member 8 mitochondrial, Mitochondrial ATP-binding cassette 1, M-ABC1, ABCB8

    Background: This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI) and is suitable for Cancer Research and drug resistance. ABCB8 is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). It has been found that ABC transporters are involved in mulitdrug resistance through their ability to contol the presence of drugs in cells. Multidrug resistance is currently being looked at in particular reference to cancer that is resistant to treatment. ABCB8 seems to have particulalrly high resistance rates in renal cancer and cancer of the central nervous system. Another significant aspect of ABCB8 is that it is a mitochondrial transporter. There are very few ABC transporters localized to the mitochondria which implies information about them could be extremely important. ABCB8 may also be localized to other parts of the cell which are yet to be determined. Anti-ABCB8 antibody is ideal for researchers nterested in Cancer Research and drug resistance.

    Gene Name: ABCB8

    ID gène
    11194
    UniProt
    Q9NUT2
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