PRKAG3 anticorps (AA 9-151)

N° du produit ABIN5611227

Détail du produit anti-PRKAG3 anticorps

Antigène: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Épitope: AA 9-151

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRKAG3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human PRKAG3 (AA: 9-151) expressed in E. coli.

Clone: 2C7A7

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: N/A, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur PRKAG3

Antigène: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Autre désignation: PRKAG3 (PRKAG3 Produits)

Synonymes: anticorps Ampkg3, anticorps prkag3-a, anticorps PRKAG3, anticorps AMPKG3, anticorps AMPKg3L, anticorps AMPKg3S, anticorps Amkg3, anticorps protein kinase AMP-activated non-catalytic subunit gamma 3, anticorps protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog, anticorps protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b, anticorps protein kinase, AMP-activated, gamma 3 non-catatlytic subunit, anticorps Prkag3, anticorps PRKAG3, anticorps prkag3.S, anticorps prkag3-b

Sujet:

Description: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

Aliases: AMPKG3

Poids moléculaire: 54.3 kDa

ID gène: 53632

HGNC: 53632

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, L'effet Warburg