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CHRNA3 anticorps (AA 32-240)

CHRNA3 Reactivité: Humain WB, ELISA, IHC, ICC, FACS, Neut Hôte: Souris Monoclonal 6D3A10 unconjugated
N° du produit ABIN5611357
  • Antigène Voir toutes CHRNA3 Anticorps
    CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))
    Épitope
    • 15
    • 9
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 32-240
    Reactivité
    • 57
    • 19
    • 18
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 56
    • 1
    Souris
    Clonalité
    • 56
    • 1
    Monoclonal
    Conjugué
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CHRNA3 est non-conjugé
    Application
    • 48
    • 21
    • 20
    • 13
    • 13
    • 7
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human CHRNA3 (AA: 32-240) expressed in E. coli.
    Clone
    6D3A10
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400, IHC: N/A
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Kulbatskii, Shenkarev, Bychkov, Loktyushov, Shulepko, Koshelev, Povarov, Popov, Peigneur, Chugunov, Kozlov, Sharonova, Efremov, Skrebitsky, Tytgat, Kirpichnikov, Lyukmanova: "Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain." dans: Frontiers in cell and developmental biology, Vol. 9, pp. 662227, (2021) (PubMed).

  • Antigène
    CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))
    Autre désignation
    CHRNA3 (CHRNA3 Produits)
    Synonymes
    anticorps LNCR2, anticorps NACHRA3, anticorps PAOD2, anticorps (a)3, anticorps A730007P14Rik, anticorps Acra-3, anticorps Acra3, anticorps cholinergic receptor nicotinic alpha 3 subunit, anticorps cholinergic receptor, nicotinic, alpha polypeptide 3, anticorps CHRNA3, anticorps Chrna3
    Sujet

    Description: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

    Aliases: LNCR2, PAOD2, NACHRA3

    Poids moléculaire
    57.5 kDa
    ID gène
    1136
    HGNC
    1136
    Pathways
    Synaptic Membrane
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