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HSPA9 anticorps (C-Term)

HSPA9 Reactivité: Humain, Rat, Souris WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN784589
  • Antigène Voir toutes HSPA9 Anticorps
    HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))
    Épitope
    • 15
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 77
    • 40
    • 25
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 71
    • 7
    Lapin
    Clonalité
    • 72
    • 6
    Polyclonal
    Conjugué
    • 38
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HSPA9 est non-conjugé
    Application
    • 59
    • 28
    • 24
    • 17
    • 13
    • 13
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects endogenous levels of total GRP75 protein.
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography
    Immunogène
    Synthetic peptide corresponding to C-Terminus of Human GRP75.
    Isotype
    IgG
    Top Product
    Discover our top product HSPA9 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at -20 °C or lower. Avoid freeze-thaw cycles.
  • Antigène
    HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))
    Autre désignation
    Grp75 / HSPA9 (HSPA9 Produits)
    Synonymes
    anticorps APG-2, anticorps HS24/P52, anticorps HSPH2, anticorps RY, anticorps hsp70, anticorps hsp70RY, anticorps CSA, anticorps GRP-75, anticorps GRP75, anticorps HSPA9B, anticorps MOT, anticorps MOT2, anticorps MTHSP75, anticorps PBP74, anticorps Hspa9a, anticorps csa, anticorps grp-75, anticorps grp75, anticorps hspa9, anticorps hspa9b, anticorps mortalin, anticorps mot, anticorps mot2, anticorps pbp74, anticorps mot-2, anticorps mthsp75, anticorps 74kDa, anticorps Csa, anticorps Grp75, anticorps Hsc74, anticorps Hsp74, anticorps Hsp74a, anticorps Mortalin, anticorps Mot-2, anticorps Mot2, anticorps Mthsp70, anticorps Pbp74, anticorps cb740, anticorps crs, anticorps wu:fc14d08, anticorps wu:fc27c10, anticorps wu:fc38a06, anticorps heat shock protein family A (Hsp70) member 4, anticorps heat shock protein family A (Hsp70) member 9, anticorps heat shock protein family A member 9, anticorps heat shock protein family A (Hsp70) member 9 S homeolog, anticorps stress-70 protein, mitochondrial, anticorps heat shock protein 9, anticorps heat shock protein Hsp9, anticorps HSPA4, anticorps HSPA9, anticorps Hspa9, anticorps hspa9.S, anticorps hspa9, anticorps LOC577721, anticorps hsp9
    Sujet
    Grp75, also known as mortalin, is a member of Hsp70 family of chaperone proteins that is not heat inducible (1, 2). Grp75 is actually induced under conditions of low glucose and other nutritional and environmental stresses. Grp75 resides primarily in the mitochondrial matrix, where it collaborates with Hsp60 in the re-folding of proteins translocated into this organelle (3, 4). Related forms may also be found in the cytosol or on the surface of the extracellular membrane. Other Grp75 functions include its ability to inactivate the tumor suppressor p53 (5). Studies have found that Grp75 is over-expressed in many tumor tissues and immortalized human cell lines, suggesting its role in the tumor formation (6). Grp75 is also implicated in cell aging, as its overexpression appears to prolong the life span of human fibroblasts (7). And finally, like its E. coli homolog DnaK (8), GRP75 possesses a cation-dependent ATPase activity considered central to its function as a chaperone (9, 10).Synonyms: 75 kDa glucose-regulated protein, HSPA9B, Heat shock 70 kDa protein 9, MOT, Mortalin, PBP74, Peptide-binding protein 74, Stress-70 protein
    ID gène
    3313
    NCBI Accession
    NP_004125
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