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MUTYH anticorps (AA 436-535)

MUTYH Reactivité: Humain WB, ELISA, IP, RNAi Hôte: Souris Monoclonal 4D10 unconjugated
N° du produit ABIN561883
  • Antigène Voir toutes MUTYH Anticorps
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    Épitope
    • 16
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 436-535
    Reactivité
    • 55
    • 38
    • 19
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 49
    • 3
    • 3
    Souris
    Clonalité
    • 52
    • 3
    Monoclonal
    Conjugué
    • 33
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MUTYH est non-conjugé
    Application
    • 30
    • 18
    • 17
    • 13
    • 13
    • 13
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), RNA Interference (RNAi)
    Fonction
    Mouse monoclonal antibody raised against a partial recombinant MUTYH.
    Séquence
    KLTYQVYGLA LEGQTPVTTV PPGARWLTQE EFHTAAVSTA MKKVFRVYQG QQPGTCMGSK RSQVSSPCSR KKPRMGQQVL DNFFRSHIST DAHSLNSAAQ
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    MUTYH (AAH03178, 436 a.a. ~ 535 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    4D10
    Isotype
    IgG1
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Komine, Shimodaira, Takao, Soeda, Zhang, Takahashi, Ishioka: "Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia Coli Strain." dans: Human mutation, Vol. 36, Issue 7, pp. 704-11, (2015) (PubMed).

    Shinmura, Goto, Tao, Kato, Suzuki, Nakamura, Matsuda, Yin, Morita, Kono, Sugimura: "Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer." dans: Oxidative medicine and cellular longevity, Vol. 2014, pp. 617351, (2014) (PubMed).

    Agustina, Hahm, Han, Tran, Chung, Park, Park, Han: "Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation." dans: BMC molecular biology, Vol. 15, pp. 17, (2014) (PubMed).

    Raetz, Xie, Kundu, Brinkmeyer, Chang, David: "Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells." dans: Carcinogenesis, Vol. 33, Issue 11, pp. 2301-9, (2012) (PubMed).

    Hahm, Chung, Agustina, Han, Yoon, Park, Kang, Park, Na, Han: "Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells." dans: Oncology letters, Vol. 4, Issue 6, pp. 1203-1208, (2012) (PubMed).

    Suzuki, Harashima, Kamiya: "Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine." dans: DNA repair, Vol. 9, Issue 5, pp. 542-50, (2010) (PubMed).

    van der Post, Kets, Ligtenberg, van Krieken, Hoogerbrugge: "Immunohistochemistry is not an accurate first step towards the molecular diagnosis of MUTYH-associated polyposis." dans: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 1, pp. 25-9, (2008) (PubMed).

  • Antigène
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    Autre désignation
    MUTYH (MUTYH Produits)
    Synonymes
    anticorps MUTYH, anticorps MGC145569, anticorps CYP2C, anticorps MYH, anticorps 5730495A01Rik, anticorps Mutyha, anticorps Mutyhalpha, anticorps Mutyhb, anticorps Mutyhbeta, anticorps Mutyhc, anticorps Myh, anticorps mutY DNA glycosylase, anticorps mutY homolog (E. coli), anticorps A/G-specific adenine DNA glycosylase-like, anticorps MUTYH, anticorps mutyh, anticorps LOC100373318, anticorps Mutyh
    Sujet
    Full Gene Name: mutY homolog (E. coli)
    Synonyms: MGC4416,MYH
    ID gène
    4595
    Pathways
    Réparation de l'ADN
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