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PDK3 anticorps (AA 174-263)

PDK3 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2B11 unconjugated
N° du produit ABIN562161
  • Antigène Voir toutes PDK3 Anticorps
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Épitope
    • 14
    • 10
    • 9
    • 9
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 174-263
    Reactivité
    • 36
    • 32
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 56
    • 2
    Souris
    Clonalité
    • 56
    • 2
    Monoclonal
    Conjugué
    • 30
    • 7
    • 6
    • 5
    • 5
    • 5
    Cet anticorp PDK3 est non-conjugé
    Application
    • 51
    • 40
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Fonction
    Mouse monoclonal antibody raised against a partial recombinant PDK3.
    Séquence
    GDTNPVHPKH IGSIDPTCNV ADVVKDAYET AKMLCEQYYL VAPELEVEEF NAKAPDKPIQ VVYVPSHLFH MLFELFKNSM RATVELYEDR
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    PDK3 (AAH15948, 174 a.a. ~ 263 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    2B11
    Isotype
    IgG2a
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Hwang, Wu, Harris: "Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet." dans: The FEBS journal, Vol. 279, Issue 10, pp. 1883-93, (2012) (PubMed).

    Jeoung, Harris: "Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice." dans: American journal of physiology. Endocrinology and metabolism, Vol. 295, Issue 1, pp. E46-54, (2008) (PubMed).

    Lu, Lin, Chen, Lai, Tsai: "Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance." dans: The Journal of biological chemistry, Vol. 283, Issue 42, pp. 28106-14, (2008) (PubMed).

  • Antigène
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Autre désignation
    PDK3 (PDK3 Produits)
    Synonymes
    anticorps pdk3, anticorps PDK3, anticorps 2610001M10Rik, anticorps AI035637, anticorps zgc:158702, anticorps pyruvate dehydrogenase kinase 3, anticorps pyruvate dehydrogenase kinase, isozyme 3a, anticorps pyruvate dehydrogenase kinase, isoenzyme 3, anticorps fragile site, 5-azacytidine type, common, fra(1)(q12), anticorps pyruvate dehydrogenase kinase, isozyme 3b, anticorps PDK3, anticorps Pdk3, anticorps pdk3a, anticorps pdk3, anticorps FRA1J, anticorps pdk3b
    Sujet
    Full Gene Name: pyruvate dehydrogenase kinase, isozyme 3
    Synonyms:
    ID gène
    5165
    Pathways
    Signalisation PI3K-Akt, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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