SPINK1
Reactivité: Humain, Singe
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
In 1x PBS, pH 7.4
Conseil sur la manipulation
Aliquot to avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Palanisamy, Tsodikov, Yan, Suleman, Rittmaster, Lucia, Chinnaiyan, Fleshner, Kunju: "Molecular profiling of ETS gene rearrangements in patients with prostate cancer registered in REDEEM clinical trial." dans: Urologic oncology, Vol. 33, Issue 3, pp. 108.e5-108.e13, (2015) (PubMed).
Ateeq, Kunju, Carskadon, Pandey, Singh, Pradeep, Tandon, Singhai, Goel, Amit, Agarwal, Dinda, Seth, Tsodikov, Chinnaiyan, Palanisamy: "Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India." dans: The Prostate, Vol. 75, Issue 10, pp. 1051-62, (2015) (PubMed).
Zhang, Wang, Hu, Wang, Yu, Wang: "The construction and proliferative effects of a lentiviral vector capable of stably overexpressing SPINK1 gene in human pancreatic cancer AsPC-1 cell line." dans: Tumour biology, (2015) (PubMed).
Smith, Palanisamy, Zuhlke, Johnson, Siddiqui, Chinnaiyan, Kunju, Cooney, Tomlins: "HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey." dans: The American journal of surgical pathology, Vol. 38, Issue 5, pp. 615-26, (2014) (PubMed).
Rink, Park, Volkmer, Xylinas, Hansen, Cha, Robinson, Hautmann, Küfer, Engel, Chun, Dahlem, Rubin, Shariat, Mosquera: "Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy." dans: Urologic oncology, Vol. 31, Issue 8, pp. 1716-24, (2013) (PubMed).
Bhalla, Kunju, Tomlins, Christopherson, Cortez, Carskadon, Siddiqui, Park, Mosquera, Pestano, Rubin, Chinnaiyan, Palanisamy: "Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 6, pp. 835-48, (2013) (PubMed).
Han, Mehra, Suleman, Tomlins, Wang, Singhal, Linetzky, Palanisamy, Zhou, Chinnaiyan, Shah: "Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 9, pp. 1176-85, (2009) (PubMed).
Tomlins, Rhodes, Yu, Varambally, Mehra, Perner, Demichelis, Helgeson, Laxman, Morris, Cao, Cao, Andrén, Fall, Johnson, Wei, Shah, Al-Ahmadie, Eastham, Eggener, Fine, Hotakainen, Stenman, Tsodikov et al.: "The role of SPINK1 in ETS rearrangement-negative prostate cancers. ..." dans: Cancer cell, Vol. 13, Issue 6, pp. 519-28, (2008) (PubMed).
Antigène
SPINK1
(serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))