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SPINK1 anticorps (AA 24-79)

SPINK1 Reactivité: Humain WB, ELISA, IHC (p), IP Hôte: Souris Monoclonal 4D4 unconjugated
N° du produit ABIN562978
  • Antigène Voir toutes SPINK1 Anticorps
    SPINK1 (serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))
    Épitope
    • 15
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 24-79
    Reactivité
    • 35
    • 16
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 45
    • 4
    • 1
    Souris
    Clonalité
    • 46
    • 4
    Monoclonal
    Conjugué
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SPINK1 est non-conjugé
    Application
    • 26
    • 26
    • 14
    • 12
    • 9
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Fonction
    Mouse monoclonal antibody raised against a partial recombinant SPINK1.
    Séquence
    DSLGREAKCY NELNGCTKIY DPVCGTDGNT YPNECVLCFE NRKRQTSILI QKSGPC
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    SPINK1 (AAH25790, 24 a.a. ~ 79 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    4D4
    Isotype
    IgG2a
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Palanisamy, Tsodikov, Yan, Suleman, Rittmaster, Lucia, Chinnaiyan, Fleshner, Kunju: "Molecular profiling of ETS gene rearrangements in patients with prostate cancer registered in REDEEM clinical trial." dans: Urologic oncology, Vol. 33, Issue 3, pp. 108.e5-108.e13, (2015) (PubMed).

    Ateeq, Kunju, Carskadon, Pandey, Singh, Pradeep, Tandon, Singhai, Goel, Amit, Agarwal, Dinda, Seth, Tsodikov, Chinnaiyan, Palanisamy: "Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India." dans: The Prostate, Vol. 75, Issue 10, pp. 1051-62, (2015) (PubMed).

    Zhang, Wang, Hu, Wang, Yu, Wang: "The construction and proliferative effects of a lentiviral vector capable of stably overexpressing SPINK1 gene in human pancreatic cancer AsPC-1 cell line." dans: Tumour biology, (2015) (PubMed).

    Smith, Palanisamy, Zuhlke, Johnson, Siddiqui, Chinnaiyan, Kunju, Cooney, Tomlins: "HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey." dans: The American journal of surgical pathology, Vol. 38, Issue 5, pp. 615-26, (2014) (PubMed).

    Rink, Park, Volkmer, Xylinas, Hansen, Cha, Robinson, Hautmann, Küfer, Engel, Chun, Dahlem, Rubin, Shariat, Mosquera: "Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy." dans: Urologic oncology, Vol. 31, Issue 8, pp. 1716-24, (2013) (PubMed).

    Bhalla, Kunju, Tomlins, Christopherson, Cortez, Carskadon, Siddiqui, Park, Mosquera, Pestano, Rubin, Chinnaiyan, Palanisamy: "Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 6, pp. 835-48, (2013) (PubMed).

    Han, Mehra, Suleman, Tomlins, Wang, Singhal, Linetzky, Palanisamy, Zhou, Chinnaiyan, Shah: "Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 9, pp. 1176-85, (2009) (PubMed).

    Tomlins, Rhodes, Yu, Varambally, Mehra, Perner, Demichelis, Helgeson, Laxman, Morris, Cao, Cao, Andrén, Fall, Johnson, Wei, Shah, Al-Ahmadie, Eastham, Eggener, Fine, Hotakainen, Stenman, Tsodikov et al.: "The role of SPINK1 in ETS rearrangement-negative prostate cancers. ..." dans: Cancer cell, Vol. 13, Issue 6, pp. 519-28, (2008) (PubMed).

  • Antigène
    SPINK1 (serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))
    Autre désignation
    SPINK1 (SPINK1 Produits)
    Synonymes
    anticorps PCTT, anticorps PSTI, anticorps Spink3, anticorps TATI, anticorps TCP, anticorps Psti, anticorps SPINK1, anticorps p12, anticorps serine peptidase inhibitor, Kazal type 1, anticorps SPINK1, anticorps Spink1
    Sujet
    Full Gene Name: serine peptidase inhibitor, Kazal type 1
    Synonyms: PCTT,PSTI,Spink3,TATI
    ID gène
    6690
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