RRAS2 anticorps (PE)

N° du produit ABIN5633276

Détail du produit anti-RRAS2 anticorps (PE)

Antigène: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RRAS2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Human TC21

Clone: EM-50

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.

Commentaires:

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur RRAS2

Antigène: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Autre désignation: R-Ras2 / TC21 (RRAS2 Produits)

Synonymes: anticorps TC21, anticorps 2610016H24Rik, anticorps C86394, anticorps Ras-related protein R-Ras2, anticorps RAS related 2, anticorps related RAS viral (r-ras) oncogene 2, anticorps related RAS viral (r-ras) oncogene homolog 2, anticorps TVAG_453070, anticorps Bm1_46660, anticorps RRAS2, anticorps Rras2

Sujet: RAS related 2,R-Ras2 / TC21 is the only member of R-Ras family of small GTPases that shows transforming activities similar to H-Ras, N-Ras, and K-Ras, and it is also structurally similar to them. R-Ras2 seems to play an important role in activating signal transduction pathways that control cell proliferation. Its mutations are associated with the growth of certain tumors, but also overexpression of the wild type form of R-Ras2 has been frequently detected in various carcinomas. Pseudogenes of R-Ras2 gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.,TC21, RRAS2

ID gène: 22800

UniProt: P62070