IL15RA anticorps

N° du produit ABIN5647166

Détail du produit anti-IL15RA anticorps

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL15RA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids I31-T174 was used as the immunogen for the IL15RA antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the IL15RA antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA (recombinant human protein): 0.1-0.5 μg/mL (BSA-free format available)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the IL15RA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur IL15RA

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Autre désignation: IL15RA (IL15RA Produits)

Synonymes: anticorps IL15RA, anticorps CD215, anticorps AA690181, anticorps IL-15RA, anticorps interleukin 15 receptor subunit alpha, anticorps interleukin 15 receptor, alpha chain, anticorps IL15RA, anticorps Il15ra

Sujet: Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene. This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

UniProt: Q13261

Pathways: Signalistation JAK/STAT