Splicing Factor 1 anticorps

N° du produit ABIN5647270

Détail du produit anti-Splicing Factor 1 anticorps

Antigène: Splicing Factor 1 (SF1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Splicing Factor 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids R160-Q266 was used as the immunogen for the SF1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SF1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the SF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Splicing Factor 1

Antigène: Splicing Factor 1 (SF1)

Autre désignation: SF1 / Splicing factor 1 (SF1 Produits)

Synonymes: anticorps BBP, anticorps D11S636, anticorps MBBP, anticorps ZCCHC25, anticorps ZFM1, anticorps ZNF162, anticorps BB094781, anticorps CW17R, anticorps MZFM, anticorps WBP4, anticorps Zfp162, anticorps CG5836, anticorps Dmel\\CG5836, anticorps cg5836, anticorps dSF1, anticorps p70, anticorps SF1, anticorps sf1, anticorps wu:fc09f06, anticorps znf162, anticorps MWD22.25, anticorps MWD22_25, anticorps SF-1, anticorps splicing factor 1, anticorps Splicing factor 1, anticorps splicing factor-like protein, anticorps nuclear receptor subfamily 5 group A member 1, anticorps splicing factor 1 S homeolog, anticorps SF1, anticorps Sf1, anticorps sf1, anticorps AT5G51300, anticorps NR5A1, anticorps sf1.S

Sujet: Splicing factor 1 also known as zinc finger protein 162 (ZFM162) is a protein that in humans is encoded by the SF1 gene. This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.

UniProt: Q15637

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location