NCR3 anticorps (AA 31-65)

N° du produit ABIN5647395

Détail du produit anti-NCR3 anticorps

Antigène: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Épitope: AA 31-65

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCR3 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 31-65 from the N-terminal region of the human protein was used as the immunogen for the NKp30 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the NKp30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western Blot: 1:1000

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NKp30 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NCR3

Antigène: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Autre désignation: NKp30 / NCR3 (NCR3 Produits)

Synonymes: anticorps MGC133750, anticorps 1C7, anticorps CD337, anticorps LY117, anticorps MALS, anticorps NKp30, anticorps Nkp30, anticorps natural cytotoxicity triggering receptor 3, anticorps NCR3, anticorps Ncr3

Sujet: Natural cytotoxicity triggering receptor 3 (NCR3), also called Natural killer cell p30-related protein (NKp30), is a cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process