AP2M1
Reactivité: Humain, Souris, Rat
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the AP2M1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
After reconstitution, the AP2M1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Antigène
AP2M1
(Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))
anticorps AP50, anticorps CLAPM1, anticorps mu2, anticorps Ap50, anticorps Clapm1, anticorps cb34, anticorps Ap2m1, anticorps dpy-23, anticorps sb:cb34, anticorps zgc:55711, anticorps zgc:85653, anticorps wu:fa97a10, anticorps ap2m1-a, anticorps ap2m1, anticorps zgc:56643, anticorps AP2M1, anticorps adaptor related protein complex 2 mu 1 subunit, anticorps adaptor-related protein complex 2, mu 1 subunit, anticorps adaptor-related protein complex 2, mu 1 subunit, a, anticorps adaptor related protein complex 2 mu 1 subunit L homeolog, anticorps adaptor-related protein complex 2, mu 1 subunit, b, anticorps AP-2 complex subunit mu-1, anticorps clathrin coat assembly protein AP50, anticorps clathrin coat assembly protein ap50, anticorps AP2M1, anticorps Ap2m1, anticorps ap2m1a, anticorps ap2m1.L, anticorps ap2m1b, anticorps ap2m1, anticorps cgd8_950, anticorps PY06523, anticorps PVX_118455, anticorps PVX_123590, anticorps CpipJ_CPIJ003697
Sujet
AP-2 complex subunit mu is a protein that in humans is encoded by the AP2M1 gene. This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.