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Mre11 anticorps

MRE11A Reactivité: Humain, Rat, Souris WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5647883
  • Antigène Voir toutes Mre11 (MRE11A) Anticorps
    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
    Reactivité
    • 74
    • 54
    • 41
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 88
    • 5
    Lapin
    Clonalité
    • 78
    • 15
    Polyclonal
    Conjugué
    • 47
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Mre11 est non-conjugé
    Application
    • 73
    • 32
    • 26
    • 26
    • 19
    • 15
    • 14
    • 11
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity purified
    Immunogène
    A recombinant human protein corresponding to amino acids S2-D239 was used as the immunogen for the MRE11 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product MRE11A Anticorps primaire
  • Indications d'application
    Optimal dilution of the MRE11 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the MRE11 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
    Autre désignation
    MRE11 (MRE11A Produits)
    Synonymes
    anticorps wu:faa63d12, anticorps zgc:64018, anticorps Mre11, anticorps Mre11b, anticorps ATLD, anticorps HNGS1, anticorps MRE11, anticorps MRE11B, anticorps MRE11 homolog A, double strand break repair nuclease, anticorps MRE11 homolog, double strand break repair nuclease, anticorps MRE11A homolog A, double strand break repair nuclease, anticorps mre11a, anticorps MRE11, anticorps Mre11a
    Sujet
    Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
    UniProt
    P49959
    Pathways
    Réparation de l'ADN
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