anticorps ACSL5, anticorps acs2, anticorps acs5, anticorps facl5, anticorps ACS2, anticorps ACS5, anticorps FACL5, anticorps 1700030F05Rik, anticorps Facl5, anticorps Acs5, anticorps zgc:92083, anticorps acyl-CoA synthetase long chain family member 5, anticorps acyl-CoA synthetase long-chain family member 5, anticorps ACSL5, anticorps acsl5, anticorps Acsl5
Sujet
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.,ACSL5,ACS2,ACS5,FACL5,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,ACSL5