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PD-L1 anticorps (PE)

PD-L1 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal 29E-2A3 PE
N° du produit ABIN5665753
  • Antigène Voir toutes PD-L1 Anticorps
    PD-L1 (CD274 (PD-L1))
    Reactivité
    • 169
    • 108
    • 63
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    Humain, Non-Human Primate
    Hôte
    • 126
    • 61
    • 17
    • 4
    • 4
    • 1
    Souris
    Clonalité
    • 108
    • 103
    • 2
    Monoclonal
    Conjugué
    • 98
    • 16
    • 12
    • 11
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
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    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Cet anticorp PD-L1 est conjugé à/à la PE
    Application
    • 138
    • 103
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    • 37
    • 28
    • 17
    • 17
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    • 15
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody 29E.2A3 recognizes an extracellular epitope of CD274 / PD-L1 (also known as B7-H1), a 40 kDa type I transmembrane protein expressed by dendritic cells, activated T cells, activated monocytes, and in various tissues, above all in heart and skeletal muscle, placenta and lung, and in many cancer cells, including T cell lymphomas, melanomas, and glioblastomas.
    Réactivité croisée (Details)
    Human, Non-Human Primates
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Full length human CD274
    Clone
    29E-2A3
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product PD-L1 Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    PD-L1 (CD274 (PD-L1))
    Autre désignation
    CD274 / PD-L1 (PD-L1 Produits)
    Synonymes
    anticorps B7-H, anticorps B7H1, anticorps PD-L1, anticorps PDCD1L1, anticorps PDCD1LG1, anticorps PDL1, anticorps A530045L16Rik, anticorps B7h1, anticorps Pdcd1l1, anticorps Pdcd1lg1, anticorps Pdl1, anticorps RGD1566211, anticorps CD274 molecule, anticorps CD274 antigen, anticorps programmed cell death 1 ligand 2, anticorps CD274, anticorps Cd274, anticorps PDCD1LG2
    Sujet
    CD274 Molecule,CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its receptor CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely.,B7H1, PDL1, PDCD1L1, PDCD1LG1, PDCD1 ligand 1, B7-H1
    ID gène
    29126
    UniProt
    Q9NZQ7
    Pathways
    Cancer Immune Checkpoints
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