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PD-L1 anticorps (CD274) (PE) Primary Antibody

PD-L1 Reactivité: Humain, Non-Human Primate FACS, Func, IHC (fro) Hôte: Souris Monoclonal 29E-2A3 PE
N° du produit ABIN5665753
$484.24
Plus shipping costs $45.00
100 tests
Destination: Etats-Unis
Envoi sous 5 à 7 jours ouvrables
  • Antigène Voir toutes PD-L1 Anticorps
    PD-L1
    Reactivité
    • 171
    • 112
    • 65
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Humain, Non-Human Primate
    Hôte
    • 130
    • 56
    • 18
    • 8
    • 2
    • 1
    Souris
    Clonalité
    • 120
    • 94
    • 1
    Monoclonal
    Conjugué
    • 101
    • 17
    • 12
    • 12
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Cet anticorp PD-L1 est conjugé à/à la PE
    Application
    • 101
    • 100
    • 69
    • 48
    • 40
    • 27
    • 17
    • 15
    • 14
    • 13
    • 10
    • 10
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    The mouse monoclonal antibody 29E.2A3 recognizes CD274 / PD-L1 (also known as B7-H1), a 40 kDa type I transmembrane protein expressed by dendritic cells, activated T cells, activated monocytes, and in various tissues, above all in heart and skeletal muscle, placenta and lung, and in many cancer cells, including T cell lymphomas, melanomas, and glioblastomas.
    Réactivité croisée (Details)
    Human, Non-Human Primates
    Immunogène
    Full length human CD274
    Clone
    29E-2A3
    Isotype
    IgG2b
  • Indications d'application
    The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
  • Antigène
    PD-L1
    Autre désignation
    CD274 / PD-L1 (PD-L1 Produits)
    Synonymes
    B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, A530045L16Rik, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1, RGD1566211, CD274 molecule, CD274 antigen, programmed cell death 1 ligand 2, CD274, Cd274, PDCD1LG2
    Sujet
    CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its ligand CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely.
    Pathways
    Cancer Immune Checkpoints
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