COMMD1 anticorps (AA 1-190)

N° du produit ABIN566862

Détail du produit anti-COMMD1 anticorps

Antigène: COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))

Épitope: AA 1-190

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp COMMD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Fonction: Mouse monoclonal antibody raised against a full length recombinant COMMD1.

Séquence: MAAGELEGGK PLSGLLNALA QDTFHGYPGI TEELLRSQLY PEVPPEEFRP FLAKMRGILK SIASADMDFN QLEAFLTAQT KKQGGITSDQ AAVISKFWKS HKTKIRESLM NQSRWNSGLR GLSWRVDGKS QSRHSAQIHT PVAIIELELG KYGQESEFLC LEFDEVKVNQ ILKTLSEVEE SISTLISQPN

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: COMMD1 (AAH22046.1, 1 a.a. ~ 190 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2A12

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-COMMD1 (ABIN566862)

OHara, Simpson, Morin, Loveridge, Williams, Novo, Stark: "p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-?B subunit." dans: Journal of cell science, Vol. 127, Issue Pt 17, pp. 3659-65, (2014) (PubMed).

Schilling, Bayer, Li, Molls, Vaupel, Multhoff: "Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1?." dans: PLoS ONE, Vol. 7, Issue 2, pp. e31110, (2012) (PubMed).

Drévillon, Tanguy, Hinzpeter, Arous, de Becdelièvre, Aissat, Tarze, Goossens, Fanen: "COMMD1-mediated ubiquitination regulates CFTR trafficking." dans: PLoS ONE, Vol. 6, Issue 3, pp. e18334, (2011) (PubMed).

Vonk, Wijmenga, Berger, van de Sluis, Klomp: "Cu,Zn superoxide dismutase maturation and activity are regulated by COMMD1." dans: The Journal of biological chemistry, Vol. 285, Issue 37, pp. 28991-9000, (2010) (PubMed).

Huang, Wu, Li: "Tumor suppressor ARF promotes non-classic proteasome-independent polyubiquitination of COMMD1." dans: The Journal of biological chemistry, Vol. 283, Issue 17, pp. 11453-60, (2008) (PubMed).

Burkhead, Morgan, Shinde, Haddock, Lutsenko: "COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with phosphatidylinositol 4,5-bisphosphate." dans: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 696-707, (2008) (PubMed).

Weiss, Lozoya, Tuma, Gotthardt, Reichert, Ehehalt, Stremmel, Füllekrug: "Copper-induced translocation of the Wilson disease protein ATP7B independent of Murr1/COMMD1 and Rab7." dans: The American journal of pathology, Vol. 173, Issue 6, pp. 1783-94, (2008) (PubMed).

Maine, Mao, Komarck, Burstein: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." dans: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).

de Bie, van de Sluis, Burstein, van de Berghe, Muller, Berger, Gitlin, Wijmenga, Klomp: "Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B." dans: Gastroenterology, Vol. 133, Issue 4, pp. 1316-26, (2007) (PubMed).

Détails sur COMMD1

Antigène: COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))

Autre désignation: COMMD1 (COMMD1 Produits)

Synonymes: anticorps C2orf5, anticorps MURR1, anticorps murr1, anticorps commd1, anticorps si:ch211-213b8.2, anticorps DDBDRAFT_0184206, anticorps DDBDRAFT_0266452, anticorps DDB_0184206, anticorps DDB_0266452, anticorps COMMD1, anticorps MGC114682, anticorps AI256843, anticorps Murr1, anticorps U2/Mu, anticorps copper metabolism domain containing 1, anticorps copper metabolism (Murr1) domain containing 1, anticorps COMM domain-containing protein 1, anticorps copper metabolism domain containing 1 L homeolog, anticorps COMM domain containing 1, anticorps COMMD1, anticorps commd1, anticorps comd1, anticorps Commd1, anticorps commd1.L

Sujet: Full Gene Name: copper metabolism (Murr1) domain containing 1
Synonyms: C2orf5,MGC27155,MURR1

ID gène: 150684

Pathways: Transition Metal Ion Homeostasis