IMPACT anticorps (AA 21-120)

N° du produit ABIN5675564

Détail du produit anti-IMPACT anticorps

Antigène: IMPACT (Impact Homolog (IMPACT))

Épitope: AA 21-120

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IMPACT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IMPACT

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur IMPACT

Antigène: IMPACT (Impact Homolog (IMPACT))

Autre désignation: IMPACT (IMPACT Produits)

Synonymes: anticorps zgc:103672, anticorps Ximpact, anticorps impact-A, anticorps RWDD5, anticorps impact-a, anticorps E430016J11Rik, anticorps impact RWD domain protein, anticorps impact, anticorps impact RWD domain protein L homeolog, anticorps impact, RWD domain protein, anticorps IMPACT, anticorps impact, anticorps EDI_298310, anticorps impact.L, anticorps Impact

Sujet:

Synonyms: Protein IMPACT, IMPACT, Imprinted and ancient gene protein homolog

Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity).

ID gène: 55364

UniProt: Q9P2X3