Ancient Ubiquitous Protein 1 anticorps (AA 229-410)

N° du produit ABIN5684097

Détail du produit anti-Ancient Ubiquitous Protein 1 anticorps

Antigène: Ancient Ubiquitous Protein 1 (Aup1)

Épitope: AA 229-410

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ancient Ubiquitous Protein 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human AUP1 (AA: 229-410) expressed in E. coli.

Clone: 7G4A6

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur Ancient Ubiquitous Protein 1

Antigène: Ancient Ubiquitous Protein 1 (Aup1)

Autre désignation: AUP1 (Aup1 Produits)

Synonymes: anticorps AA589454, anticorps wu:fc37d06, anticorps zgc:73323, anticorps zgc:77755, anticorps AUP1, lipid droplet regulating VLDL assembly factor, anticorps ancient ubiquitous protein 1, anticorps ancient ubiquitous protein 1 S homeolog, anticorps AUP1, anticorps aup1, anticorps Aup1, anticorps aup1.S

Sujet: The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.

Poids moléculaire: 53 kDa

ID gène: 550

HGNC: 27180