CHRNB3 anticorps (AA 25-232)

N° du produit ABIN5684151

Détail du produit anti-CHRNB3 anticorps

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Épitope: AA 25-232

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CHRNB3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human CHRNB3 (AA: extra 25-232) expressed in E. coli.

Clone: 4C1H2

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur CHRNB3

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Autre désignation: CHRNB3 (CHRNB3 Produits)

Synonymes: anticorps 5730417K16Rik, anticorps Acrb3, anticorps NACHR, anticorps CHRNB3, anticorps chrnb3, anticorps cholinergic receptor nicotinic beta 3 subunit, anticorps neuronal acetylcholine receptor subunit beta-3, anticorps cholinergic receptor, nicotinic, beta polypeptide 3, anticorps cholinergic receptor, nicotinic beta 3 L homeolog, anticorps cholinergic receptor, nicotinic beta 3, anticorps cholinergic receptor, nicotinic, beta 3b (neuronal), anticorps cholinergic receptor, nicotinic, beta polypeptide 3a, anticorps CHRNB3, anticorps CpipJ_CPIJ012638, anticorps Chrnb3, anticorps chrnb3.L, anticorps chrnb3, anticorps chrnb3b, anticorps chrnb3a

Sujet: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N-terminal extracellular domain followed by 3 conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region.

Poids moléculaire: 52.7 kDa

ID gène: 1142

HGNC: 5169