APOBEC3B anticorps (AA 20-70)

N° du produit ABIN5689877

Détail du produit anti-APOBEC3B anticorps

Antigène: APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))

Épitope: AA 20-70

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOBEC3B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: APOBEC3B antibody is human, mouse and rat reactive . At least three isoforms of APOBEC3B are known to exist, this antibody will detect all three. APOBEC3B antibody may cross-react with APOBEC3D.

Purification: APOBEC3B antibody is affinity chromatography purified via peptide column.

Immunogène: APOBEC3B antibody was raised against a 14 amino acid peptide near the amino terminus of human APOBEC3B.

The immunogen is located within amino acids 20 - 70 of APOBEC3B.

Isotype: IgG

Information d'application

Indications d'application: APOBEC3B antibody can be used for detection of APOBEC3B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: APOBEC3B Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: APOBEC3B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur APOBEC3B

Antigène: APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))

Autre désignation: APOBEC3B (APOBEC3B Produits)

Synonymes: anticorps A3B, anticorps APOBEC1L, anticorps ARCD3, anticorps ARP4, anticorps DJ742C19.2, anticorps PHRBNL, anticorps bK150C2.2, anticorps APOBEC3B, anticorps Apobec3, anticorps Apobec3f, anticorps APOBEC3F, anticorps APOBEC3Z2, anticorps APOBEC3Z3, anticorps apolipoprotein B mRNA editing enzyme catalytic subunit 3B, anticorps APOBEC3B, anticorps Apobec3b

Sujet: The Apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like (APOBEC) 3 is a multi-isoform member of the cytosine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates (1). Similar to TRIM5? which targets incoming retroviral capsids, APOBEC3 plays a major role in cellular defense against retroviral infection (2,3). APOBEC3B has also been shown to be upregulated in several cancers, it is thought that APOBEC3B-catalyzed genomic uracil lesions are responsible for a large proportion of mutations in multiple distinct cancers (4).

Poids moléculaire: Predicted: 42 kDa

Observed: 48 kDa

ID gène: 9582

NCBI Accession: NP_004891

UniProt: Q9UH17