SKIV2L anticorps (AA 260-310)

N° du produit ABIN5689978

Détail du produit anti-SKIV2L anticorps

Antigène: SKIV2L (Superkiller Viralicidic Activity 2-Like (SKIV2L))

Épitope: AA 260-310

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKIV2L est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: GPRASP1 antibody is human and mouse reactive. This antibody is predicted to not cross-react with GPRASP2.

Purification: GPRASP1 antibody is affinity chromatography purified via peptide column.

Immunogène: GPRASP1 antibody was raised against a 15 amino acid peptide near the amino terminus of human GPRASP1.

The immunogen is located within amino acids 260 - 310 of GPRASP1.

Isotype: IgG

Information d'application

Indications d'application: GPRASP1 antibody can be used for detection of GPRASP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GPRASP1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: GPRASP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SKIV2L

Antigène: SKIV2L (Superkiller Viralicidic Activity 2-Like (SKIV2L))

Autre désignation: SKI2W (SKIV2L Produits)

Synonymes: anticorps 4930534J06Rik, anticorps AW214248, anticorps Ddx13, anticorps SKI, anticorps Ski2w, anticorps 170A, anticorps DDX13, anticorps HLP, anticorps SKI2, anticorps SKI2W, anticorps SKIV2, anticorps THES2, anticorps superkiller viralicidic activity 2-like (S. cerevisiae), anticorps Ski2 like RNA helicase, anticorps Skiv2l, anticorps SKIV2L

Sujet: The G protein-coupled receptor associated sorting protein 1 (GPRASP1) is a member of the GPRASP family and is thought to modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors (1,2). GPRASP1 interacts with receptors such as the D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CNR1) and targets these proteins for degradation in lysosomes (2). Recently, it has been shown that increased GPRASP1 levels may act as a potential biomarker for breast cancer (3).

Poids moléculaire: Predicted: 153 kDa

Observed: 150 kDa

ID gène: 9737

NCBI Accession: NP_001171656

UniProt: Q5JY77