MLXIP anticorps (N-Term)
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- Antigène Voir toutes MLXIP Anticorps
- MLXIP (MLX Interacting Protein (MLXIP))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MLXIP est non-conjugé
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Application
- ELISA, Western Blotting (WB)
- Purification
- MLXIP Antibody is affinity chromatography purified via peptide column.
- Immunogène
- MLXIP antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human MLXIP.
- Isotype
- IgG
- Top Product
- Discover our top product MLXIP Anticorps primaire
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- Indications d'application
- MLXIP antibody can be used for Western blot at 1 - 2 μ,g/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- MLXIP Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- MLXIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- MLXIP (MLX Interacting Protein (MLXIP))
- Autre désignation
- MLXIP (MLXIP Produits)
- Synonymes
- anticorps MGC83884, anticorps si:ch211-110p13.4, anticorps MIR, anticorps MONDOA, anticorps bHLHe36, anticorps AW228700, anticorps B930074I24, anticorps Mir, anticorps mKIAA0867, anticorps RGD1560774, anticorps MLX interacting protein, anticorps MLX interacting protein L homeolog, anticorps MLXIP, anticorps mlxip.L, anticorps mlxip, anticorps Mlxip
- Sujet
- MLXIP Antibody: MLXIP is a member of the Myc superfamily of transcription factors and functions as part of a heterodimer with Max-like protein X (MLX) to activate transcription (1). MLXIP contributes to the regulation of glucose homeostasis as the MLXIP/MLX heterodimer activates expression of thioredoxin-interacting protein (TXNIP), a potent inhibitor of cellular glucose uptake and aerobic glycolysis. The mammalian target of rapamycin (mTOR) suppresses the activation of the TXNIP pathway by binding to MLXIP, thereby preventing the MLXIP/MLX heterodimer formation (2). MLXIP interaction with Myc may also be involved in metabolic reprogramming and tumorigenesis (3).
- Poids moléculaire
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Predicted: 20 kDa
Observed: 21 kDa - ID gène
- 22877
- NCBI Accession
- NP_055753
- UniProt
- Q9HAP2
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