CHM anticorps (AA 193-380)
-
- Antigène Voir toutes CHM Anticorps
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
-
Épitope
- AA 193-380
-
Reactivité
- Humain, Rat, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CHM est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
- Rabbit IgG polyclonal antibody for CHM detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- Immunogène
- E. coli-derived human CHM recombinant protein (Position: A193-Q380).
- Top Product
- Discover our top product CHM Anticorps primaire
-
-
- Indications d'application
-
Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
-
- Antigène
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
- Autre désignation
- CHM (CHM Produits)
- Synonymes
- anticorps CHM, anticorps REP1, anticorps DXS540, anticorps GGTA, anticorps HSD-32, anticorps REP-1, anticorps TCD, anticorps DKFZp459K2154, anticorps tcd, anticorps ggta, anticorps rep-1, anticorps dxs540, anticorps hsd-32, anticorps MGC68578, anticorps Rep-1, anticorps chm, anticorps chm-a, anticorps chm-b, anticorps chml, anticorps CHM, Rab escort protein 1, anticorps choroideremia (Rab escort protein 1), anticorps choroideremia (Rab escort protein 1) L homeolog, anticorps choroidermia (RAB escort protein 1), anticorps choroideremia (Rab escort protein 1) S homeolog, anticorps CHM, anticorps chm, anticorps chm.L, anticorps Chm, anticorps chm.S
- Sujet
-
Synonyms: Rab proteins geranylgeranyltransferase component A 1, Choroideremia protein, Rab escort protein 1, REP-1, TCD protein, CHM, REP1, TCD
Background: Rab escort protein 1 (REP1) also known as rab proteins geranylgeranyltransferase component A 1 is an enzyme that in humans is encoded by the CHM gene. This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.
- UniProt
- P24386
- Pathways
- Sensory Perception of Sound
-