SART3 anticorps

N° du produit ABIN5698376

Détail du produit anti-SART3 anticorps

Antigène: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SART3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunogène: squamous cell carcinoma antigen recognized by T cells 3

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07612(SART3 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur SART3

Antigène: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Autre désignation: SART3 (SART3 Produits)

Synonymes: anticorps SART3, anticorps DKFZp469J2418, anticorps si:ch211-191d15.4, anticorps wu:fc51h03, anticorps DSAP1, anticorps P100, anticorps RP11-13G14, anticorps TIP110, anticorps p110, anticorps p110(nrb), anticorps AU045857, anticorps mKIAA0156, anticorps squamous cell carcinoma antigen recognized by T-cells 3, anticorps squamous cell carcinoma antigen recognized by T-cells 3 L homeolog, anticorps squamous cell carcinoma antigen recognized by T cells 3, anticorps SART3, anticorps sart3, anticorps sart3.L, anticorps Sart3

Sujet: Synonyms:DSAP1, hSART 3, KIAA0156, P100, p110, p110(nrb), RP11 13G14, SART 3, SART3, TIP110, Background:U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation(PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites(PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly(PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair(PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC(By similarity).

ID gène: 9733

UniProt: Q15020

Pathways: Ribonucleoprotein Complex Subunit Organization