UPF3A anticorps

N° du produit ABIN5698666

Détail du produit anti-UPF3A anticorps

Antigène: UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UPF3A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: UPF3 regulator of nonsense transcripts homolog A (yeast)

Isotype: IgG

Information d'application

Indications d'application: WB : 1:500-1:5000,IHC:1:20-1:200,IF:1:20-1:200

Commentaires:

human testis tissue were subjected to SDS PAGE followed by western blot with FNab09271(UPF3A antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur UPF3A

Antigène: UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))

Autre désignation: UPF3A (UPF3A Produits)

Synonymes: anticorps 2600001C03Rik, anticorps 4930546M19Rik, anticorps RENT3A, anticorps UPF3, anticorps UPF3A, anticorps HUPF3A, anticorps si:dkey-21o13.6, anticorps UPF3 regulator of nonsense transcripts homolog A (yeast), anticorps UPF3A, regulator of nonsense mediated mRNA decay, anticorps Upf3a, anticorps UPF3A, anticorps upf3a

Sujet: Synonyms:HUpf3, HUPF3A, RENT3A, UPF3, UPF3A Background:Involved in nonsense-mediated decay(NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex(EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex(including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. However, UPF3A is shown to be only marginally active in NMD as compared to UPF3B. Binds spliced mRNA upstream of exon-exon junctions. In vitro, weakly stimulates translation.

Poids moléculaire: 123kDa

ID gène: 65110

UniProt: Q9H1J1