PQBP1 anticorps

N° du produit ABIN5698975

Détail du produit anti-PQBP1 anticorps

Antigène: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PQBP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: polyglutamine binding protein 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur PQBP1

Antigène: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Autre désignation: PQBP1 (PQBP1 Produits)

Synonymes: anticorps PQBP1, anticorps MRX55, anticorps MRXS3, anticorps MRXS8, anticorps NPW38, anticorps RENS1, anticorps SHS, anticorps PQBP-1, anticorps Sfc2, anticorps npw38, anticorps polyglutamine binding protein 1, anticorps PQBP1, anticorps Pqbp1

Sujet: Synonyms:NPW38 Background:Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species(PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.

ID gène: 10084

UniProt: O60828

Pathways: Ribonucleoprotein Complex Subunit Organization