DOC2B anticorps

N° du produit ABIN5700796

Détail du produit anti-DOC2B anticorps

Antigène: DOC2B (Double C2-Like Domains, beta (DOC2B))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOC2B est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Immunogène: double C2-like domains, beta

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur DOC2B

Antigène: DOC2B (Double C2-Like Domains, beta (DOC2B))

Autre désignation: DOC2B (DOC2B Produits)

Synonymes: anticorps DOC2BL, anticorps multiple C2 and transmembrane domain-containing protein 1-like, anticorps double C2 domain beta, anticorps double C2-like domains, beta, anticorps double C2, beta, anticorps LOC100369196, anticorps DOC2B, anticorps doc2b, anticorps Doc2b

Sujet: Synonyms:DOC2BL Background:Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes(By similarity).

Poids moléculaire: 46 kDa

ID gène: 8447

UniProt: Q14184

Pathways: Positive Regulation of Peptide Hormone Secretion