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MACF1 anticorps

MACF1 Reactivité: Humain, Souris, Rat ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5701487
  • Antigène Voir toutes MACF1 Anticorps
    MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 9
    • 2
    Lapin
    Clonalité
    • 10
    • 1
    Polyclonal
    Conjugué
    • 6
    • 2
    • 2
    • 1
    Cet anticorp MACF1 est non-conjugé
    Application
    • 9
    • 6
    • 4
    • 3
    • 2
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Immunogène
    microtubule-actin crosslinking factor 1
    Isotype
    IgG
    Top Product
    Discover our top product MACF1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze / thaw cycles.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))
    Autre désignation
    MACF1 (MACF1 Produits)
    Synonymes
    anticorps ABP620, anticorps ACF7, anticorps MACF, anticorps OFC4, anticorps Acf7, anticorps Aclp7, anticorps R74989, anticorps mKIAA0465, anticorps MACF1, anticorps fc46g01, anticorps wu:fc46g01, anticorps si:rp71-45k5.7, anticorps acf7, anticorps macf, anticorps ofc4, anticorps abp620, anticorps DKFZp469K2016, anticorps Kiaa0754, anticorps mKIAA0754, anticorps microtubule-actin crosslinking factor 1, anticorps microtubule-actin crosslinking factor 1a, anticorps microtubule-actin cross-linking factor 1, anticorps dual specificity protein kinase CLK3, anticorps microtubule-actin cross-linking factor 1, isoforms 1/2/3/5, anticorps KIAA0754, anticorps RIKEN cDNA D830031N03 gene, anticorps MACF1, anticorps Macf1, anticorps macf1a, anticorps macf1, anticorps LOC100175356, anticorps LOC100514848, anticorps LOC100550622, anticorps KIAA0754, anticorps D830031N03Rik
    Sujet
    Synonyms:ABP620, ACF7, KIAA0465, KIAA1251 Background:Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex(composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions(FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells(By similarity).
    ID gène
    23499
    UniProt
    Q9UPN3
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