Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

AKAP8L anticorps

AKAP8L Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5702022
  • Antigène Voir toutes AKAP8L Anticorps
    AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
    Reactivité
    • 39
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 39
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AKAP8L est non-conjugé
    Application
    • 29
    • 18
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Immunogène
    A kinase (PRKA) anchor protein 8-like
    Isotype
    IgG
    Top Product
    Discover our top product AKAP8L Anticorps primaire
  • Indications d'application
    WB :1:200-1:2000,IF:1:20-200
    Commentaires

    PC-3 cells were subjected to SDS PAGE followed by western blot with FNab00258( AKAP8L Antibody) at dilution of 1:300

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze / thaw cycles.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
    Autre désignation
    AKAP8L (AKAP8L Produits)
    Synonymes
    anticorps HA95, anticorps HAP95, anticorps NAKAP, anticorps NAKAP95, anticorps Nakap95, anticorps zgc:85966, anticorps AKAP8L, anticorps A-kinase anchoring protein 8 like, anticorps A kinase (PRKA) anchor protein 8-like, anticorps A-kinase anchoring protein 8 like L homeolog, anticorps AKAP8L, anticorps Akap8l, anticorps akap8l, anticorps akap8l.L
    Sujet
    Synonyms:A kinase anchor protein 8 like, AKAP8 like protein, AKAP8L, DKFZp434L0650, HA95, HAP95, Helicase A binding protein 95, Homologous to AKAP95 protein, NAKAP, NAKAP95, Neighbor of AKAP95 Background:Could play a role in constitutive transport element(CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export(PubMed:10748171, PubMed:11402034). Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA(PubMed:10761695, PubMed:11884601). May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis(PubMed:11034899). May regulate the initiation phase of DNA replication when associated with TMPO isoform Beta(PubMed:12538639). Required for cell cycle G2/M transition and histone deacetylation during mitosis. In mitotic cells recruits HDAC3 to the vicinity of chromatin leading to deacetylation and subsequent phosphorylation at 'Ser-10' of histone H3, in this function seems to act redundantly with AKAP8(PubMed:16980585). May be involved in regulation of pre-mRNA splicing(PubMed:17594903). (Microbial infection) In case of EBV infection, may target PRKACA to EBNA-LP-containing nuclear sites to modulate transcription from specific promoters(PubMed:11884601). Can synergize with DHX9 to activate the CTE-mediated gene expression of type D retroviruses(PubMed:11402034). In case of HIV-1 infection, involved in the DHX9-promoted annealing of host tRNA(Lys3) to viral genomic RNA as a primer in reverse transcription, in vitro negatively regulates DHX9 annealing activity(PubMed:25034436).
    Poids moléculaire
    72kDa
    ID gène
    26993
    UniProt
    Q9ULX6
    Pathways
    SARS-CoV-2 Protein Interactome
Vous êtes ici:
Support technique