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BRD8 anticorps

BRD8 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal unconjugated
N° du produit ABIN5702375
  • Antigène Voir toutes BRD8 Anticorps
    BRD8 (Bromodomain Containing 8 (BRD8))
    Reactivité
    • 25
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 24
    • 2
    Souris
    Clonalité
    • 24
    • 2
    Monoclonal
    Conjugué
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BRD8 est non-conjugé
    Application
    • 12
    • 8
    • 7
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Immunogène
    bromodomain containing 8
    Isotype
    IgG1
    Top Product
    Discover our top product BRD8 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze / thaw cycles.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    BRD8 (Bromodomain Containing 8 (BRD8))
    Autre désignation
    BRD8 (BRD8 Produits)
    Synonymes
    anticorps SMAP, anticorps SMAP2, anticorps p120, anticorps 2610007E11Rik, anticorps 4432404P07Rik, anticorps bromodomain containing 8, anticorps BRD8, anticorps Brd8
    Sujet
    Synonyms:SMAP, SMAP2 Background:May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors(NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase(HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
    Poids moléculaire
    120 kDa
    ID gène
    10902
    UniProt
    Q9H0E9
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