BBS9 anticorps

N° du produit ABIN5702573

Détail du produit anti-BBS9 anticorps

Antigène: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BBS9 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Immunogène: Bardet-Biedl syndrome 9

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab00825(BBS9 antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur BBS9

Antigène: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Autre désignation: BBS9 (BBS9 Produits)

Synonymes: anticorps b1, anticorps B1, anticorps C18, anticorps D1, anticorps PTHB1, anticorps RGD1308472, anticorps E130103I17Rik, anticorps Bardet-Biedl syndrome 9, anticorps bardet-biedl syndrome 9, anticorps Bardet-Biedl syndrome 9 (human), anticorps BBS9, anticorps bbs9, anticorps Bbs9

Sujet: Synonyms:PTHB1 Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.

Poids moléculaire: 60 kDa

ID gène: 27241

UniProt: Q3SYG4

Pathways: Signalisation Hedgehog