Histone Cluster 3, H3 (HIST3H3) anticorps

N° du produit ABIN5702948

Détail du produit

Antigène: Histone Cluster 3, H3 (HIST3H3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogène: histone cluster 2, H3a

Isotype: IgG

Information d'application

Indications d'application: WB : 1:500-1:5000 IHC : 1:50-1:200 IF : 1:20-1:200

Commentaires:

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03890(Histone-H3 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détail du antigène

Antigène: Histone Cluster 3, H3 (HIST3H3)

Autre désignation: Histone-H3 (HIST3H3 Produits)

Synonymes: anticorps H3.4, anticorps H3/g, anticorps H3FT, anticorps H3t, anticorps H3/A, anticorps H3FA, anticorps H3.2-221, anticorps Hist1, anticorps histone cluster 3 H3, anticorps histone cluster 1 H3 family member a, anticorps histone cluster 3, H3, anticorps histone cluster 1, H3f, anticorps HIST3H3, anticorps HIST1H3A, anticorps Hist1h3f

Sujet: Synonyms:H3/n, H3/o, H3F2, H3FM, HIST2H3A, HIST2H3C, HIST2H3D, histone cluster 2, H3a, Histone H3, Histone H3.2, Histone H3/m, Histone H3/o Background:HIST2H3A,histone cluster 2, H3a.It is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST2H3A is Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation.

Poids moléculaire: 15-17 kDa

UniProt: Q71DI3