EPH Receptor B4 anticorps

N° du produit ABIN5703803

Détail du produit anti-EPH Receptor B4 anticorps

Antigène: EPH Receptor B4 (EPHB4)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Immunogène: EPH receptor B4

Isotype: IgG

Information d'application

Indications d'application: WB : 1:500-1:5000 IHC : 1:20-1:200

Commentaires:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab02807( EPHB4 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur EPH Receptor B4

Antigène: EPH Receptor B4 (EPHB4)

Autre désignation: EPHB4 (EPHB4 Produits)

Synonymes: anticorps HTK, anticorps MYK1, anticorps TYRO11, anticorps htk, anticorps myk1, anticorps ephB4a, anticorps tyro11, anticorps ephb4b, anticorps MGC130997, anticorps AI042935, anticorps Htk, anticorps MDK2, anticorps Myk1, anticorps Tyro11, anticorps cb646, anticorps ephB4, anticorps rtk5, anticorps EphB-rtk8, anticorps cb417, anticorps rtk8, anticorps EPH receptor B4, anticorps EPH receptor B4 L homeolog, anticorps EPH receptor B4 S homeolog, anticorps Eph receptor B4, anticorps eph receptor B4a, anticorps eph receptor B4b, anticorps EPHB4, anticorps ephb4.L, anticorps ephb4.S, anticorps ephb4, anticorps Ephb4, anticorps ephb4a, anticorps ephb4b

Sujet: Synonyms:EPH receptor B4, EPHB4, Ephrin type B receptor 4, HTK, MYK1, TYRO11, Tyrosine protein kinase TYRO11 Background:Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

Poids moléculaire: 110 kDa

ID gène: 2050

UniProt: P54760

Pathways: Signalisation RTK