PARD3 anticorps

N° du produit ABIN5704096

Détail du produit anti-PARD3 anticorps

Antigène: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARD3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Immunogène: par-3 partitioning defective 3 homolog (C. elegans)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06146(PARD3 antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur PARD3

Antigène: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Autre désignation: PARD3 (PARD3 Produits)

Synonymes: anticorps ASIP, anticorps Baz, anticorps PAR3, anticorps PAR3alpha, anticorps PARD-3, anticorps PARD3A, anticorps SE2-5L16, anticorps SE2-5LT1, anticorps SE2-5T2, anticorps Par3, anticorps AA960621, anticorps AI256638, anticorps D8Ertd580e, anticorps PAR-3, anticorps Pard3a, anticorps asip, anticorps bazooka, anticorps par-3, anticorps par3, anticorps pard3, anticorps par-3 family cell polarity regulator, anticorps partitioning defective 3 homolog, anticorps par-3 family cell polarity regulator alpha, b, anticorps par-3 family cell polarity regulator S homeolog, anticorps PARD3, anticorps Pard3, anticorps LOC100551156, anticorps LOC100473914, anticorps pard3, anticorps pard3ab, anticorps pard3.S

Sujet: Synonyms:ASIP, Baz, Bazooka, CTCL tumor antigen se2 5, FLJ21015, PAR 3, PAR3, PAR3 alpha, PAR3A, PAR3alpha, PARD 3, PARD3, PARD3A, SE2 5L16, SE2 5LT1, SE2 5T2 Background:Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination(By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.PARD3 has three splice isoforms at 100 kDa, 150 kDa, and 180 kDa. This polyclonal antibody raised against C-terminal 281 amino acids of human PARD3 recognizes these three isoforms.

ID gène: 56288

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization